GB Sciences Inc (OTCMKTS:GBLX) is encouraged by the PD (Parkinson’s disease) formulations effect on patients suffering from the loss of dopamine-producing neurons. Halifax based NRC’s Dr. Lee Ellis is performing the study using the PD formulations of GB Sciences on people suffering from low levels of dopamine-producing neurons. The company will conduct the final study on the mechanism of action using these PD formulations that help to provide relief for patients.
Human clinical trial begins next year
Director and Chief Scientific Officer of GB Sciences, Dr. Andrea Small-Howard, said the mixtures of GB Sciences are effective. Its most effective mixture has shown positive results in reducing the behavioral changes and brings back to the normal level when tests are conducted on animals. According to CSO, the PD formulation has shown almost negligible side effects. The company will include these preclinical results as a proof of concept when applying for investigational new drug application with the FDA. Following the nod of the US FDA, GB Sciences will begin a human clinical trial next year.
Reduced dopamine levels cause movement disorders
Reduced dopamine levels in the brain are responsible for movement disorders. The PD formulations, developed by GB Sciences, will protect the dopamine-producing neurons. It will activate the surviving to increase secretion of dopamine and compensates for the reduction in dopamine-producing neurons. The company will examine these effects of PD formulation in the final study.
Director and President of GB Sciences, Dr. Michael Farley, said positive preclinical trial shows CBD containing complex mixtures expect to cure Parkinson’s disease symptomology. He further said the company would conduct the human clinical trials using these effective PD formulations in 2020.
Signs a binding LOI to sell membership interests
GB Sciences has signed a binding LOI to divest 75% of the membership interests in its Las Vegas, Nevada production operation, and cultivation. Following the deal, GB Sciences will reduce its operational spending and produce working capital. It will also generate sufficient cash flow to concentrate on wellness and biopharmaceutical assets. Following this deal, GB Sciences will exit from cannabis production and cultivation. The company will receive $6 million that includes $3 million in cash and the balance promissory note.